As we head into the heart of winter, influenza activity across Missouri remains very high, with case counts and hospital visits continuing to rise. According to the latest report from the Missouri Department of Health and Senior Services (DHSS), flu activity is significantly elevated compared with baseline levels this season and we are seeing the impact in communities across the state.
Nationwide the CDC estimates between October 1, 2025, through December 20, 2025, there have been 7.5 million – 13 million flu illnesses, 3.5 million – 6 million flu medical visits, 81,000-160,000 flu hospitalizations, and 3,100-17,000 flu deaths. This data is preliminary and are updated weekly throughout the season.
Key Highlights This Season
- Emergency department visits for influenza-like illnesses and postive lab test are well above typical baseline levels.
- There have been FIVE influenza-associated deaths in Missouri reported as of week 51, reflecting the severity of this season and the risk flu can pose, especially to our vulnerable populations.
- Influenza A continues to be the most frequently reported strain circulating this season, comprising the vast majority of positive cases.
Influenza A viruses often spread quickly and can cause more severe symptoms in some individuals. While both Influenza A and B can make people sick, A strains typically predominate in most flu seasons, including this one.
Why This Matters
The Flu isn’t just a “bad cold”. It can lead to serious health outcomes, including:
- Hospitalization
- Complications for people with chronic health conditions
- Severe illness in seniors and young children
- Death
This is why we are emphasizing prevention and protective steps, especially with activity being so high.
How You Can Protect Yourself and Your Family
- Get vaccinated if you haven’t already. Flu shots are recommended for everyone 6 months and older.
- Practice good hygiene, wash hands often with soap and water.
- Cover coughs and sneezes with a tissue or your elbow
- Stay at home when you are sick to prevent spreading the virus.
- Avoid close contact with those who are ill.
Flu vaccines not only help decrease your risk of becoming sick but also help reduce the severity of illness in people who do get sick.
Stay Informed with Weekly Updates
Flu activity changes week to week. For the latest influenza data, trends, and county-level statistics, follow Missouri DHSS’s influenza dashboard:
Influenza | Influenza Surveillance Report | Health & Senior Services
To read the full DHSS flu activity bulletin referenced here and learn more about this season’s trend and prevention recommendations, check out the official release:
Missouri health officials urge flu prevention amid seasonal uptick
To follow the nationwide estimated flu disease burden for this season, check out the CDC’s page here:
Preliminary Estimated Flu Disease Burden 2025-2026 Flu Season | Flu Burden | CDC
